Is your spouse’s condition affecting you where you’re not able to function? Or is your spouse physically, emotionally or sexually abusing you? For me, it wasn’t abuse but it was where I was not able to function. I was having trouble going to work (where I was the one with a stable job) and I was crying multiple times throughout the day. Not being able to function for me was the sign that the current situation couldn’t continue, and something needed to change. This is, of course, one of the last resorts but may need to be leveraged. It’s important if you separate that you have a plan to get back together; otherwise, you’ll stay apart. Make sure to be working with wise people around you, including a personal therapist and possibly a marriage therapist as well.